Cyclocytidine hydrochloride
Cyclocytidine hydrochloride
CAS: 10212-25-6
Molecular Formula: C9H11N3O4· HCl
Cyclocytidine hydrochloride - Names and Identifiers
| Name | Cyclocytidine hydrochloride |
| Synonyms | Cyclocytidine hydrochloride 2,2'-O-Cyclocytidine Hydrochloride 2,2'-dihydro-1-beta-D-arabinofuranosylcytosine hydrochloride 2,2'-Anhydro-1-beta-D-arabinofuranosylcytosine hydrochloride |
| CAS | 10212-25-6 |
| EINECS | 233-515-6 |
| InChI | InChI=1/C9H11N3O4.ClH/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8;/h1-2,4,6-8,10,13-14H,3H2;1H/t4-,6-,7+,8-;/m1./s1 |
| InChIKey | KZOWNALBTMILAP-JBMRGDGGSA-N |
Cyclocytidine hydrochloride - Physico-chemical Properties
| Molecular Formula | C9H11N3O4· HCl |
| Molar Mass | 261.66 |
| Melting Point | 269-270℃ |
| Boling Point | 442℃ at 760 mmHg |
| Specific Rotation(α) | -21 ° (C=2, H2O) |
| Appearance | Morphology Powder |
| Color | White |
| Merck | 14,629 |
| Storage Condition | Inert atmosphere,2-8°C |
| Sensitive | Easily absorbing moisture |
| MDL | MFCD00012636 |
| Physical and Chemical Properties | Chemical quality This product is white needle-like crystal or crystalline powder; odorless; soluble in water, slightly soluble in methanol and ethanol, almost insoluble in ether, benzene and chloroform; mp256-262 ℃ (decomposition). specific rotation -20 ° -23 °(c = 2 g/ml,H2O). |
| Use | Effective for all types of acute leukemia and meningeal leukemia |
Cyclocytidine hydrochloride - Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 2 |
| RTECS | LV2615000 |
| HS Code | 29213000 |
Cyclocytidine hydrochloride - Upstream Downstream Industry
Cyclocytidine hydrochloride - Nature
Open Data Verified Data
- This product is white needle-like crystalline powder; Odorless. It is soluble in water, slightly soluble in methanol and ethanol, and almost insoluble in ether. Melting Point 256~262 °c (decomposition). Specific optical rotation -20. ~- 23. (c A 2,H2 0).
- This product is a glycidyl compound of cytarabine, which is characterized by being stable to cytosine deaminase and also stable to other metabolic enzymes. Conversion to cytarabine triphosphate within the cell interferes with DNA polymerase and DNA synthesis. This product is a cell cycle specific drug, mainly in the S phase, the G1/S, S/G2 boundary has a delay effect. Malignant lymphoma has a certain therapeutic effect.
Last Update：2024-01-02 23:10:35
Cyclocytidine hydrochloride - Use
Open Data Verified Data
antineoplastic agents.
Last Update：2022-01-01 11:12:43
Cyclocytidine hydrochloride - Safety
Open Data Verified Data
- the adverse reactions were similar to those of cytarabine, but mild. Has bone marrow suppression effect. White blood cells, thrombocytopenia, more than 2 to 4 weeks after administration, generally not serious. Large dosage often occurs parotid pain, local cold compress can relieve pain. Sometimes visible salivation, sometimes visible orthostatic hypotension, Conjunctival Congestion, nasal mucosa swelling, individual patients with Head Pain, rash. Occasionally, it may cause transient pulmonary inflammation. Hemogram should be strictly checked during medication.
- under shading, sealed and preserved.
Last Update：2022-01-01 11:12:44
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Mobile: 0086 189 4982 3763
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Multiple Specifications
Product Name: 2,2'-Anhydrocytidine HCl Request for quotationCAS: 10212-25-6
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View History
Raw Materials for Cyclocytidine hydrochloride
Cation exchange resin,strong acidic styrene
Anion exchange resin,strong basic quarternary ammoniumⅠ
FERROUS GLUCONATE BP/USP
Ammonia
Acetic acid
Hydrochloric acid
Imidazole
Phosphorus pentasulfide
Anion exchange resin,strong basic quarternary ammoniumⅠ
FERROUS GLUCONATE BP/USP
Ammonia
Acetic acid
Hydrochloric acid
Imidazole
Phosphorus pentasulfide